Pigs as universal flu vaccine models
Researchers from The Pirbright Institute collaborated with the University of Oxford and the National Institutes of Health, USA, to show that S-FLU, a universal flu vaccine candidate, induces different immune responses in pigs compared to ferrets, raising the possibility that the ferrets may not give the whole picture and that pigs may more faithfully represent human influenza disease. The team also identified a type of T cell in pigs for the first time, which are able to rapidly help fight respiratory infections. The S-FLU aerosol vaccine, developed by Alain Townsend at Oxford, is a weakened strain of flu virus which is designed to trigger a response from T cells that are able to react to multiple strains of flu. This differs from conventional flu vaccines which activate antibodies that only respond to the strain contained in the vaccine. The research, published in theJournal of Immunology, demonstrated that when pigs received the S-FLU aerosol vaccine, the newly identified T cells were activated when challenged with a flu virus of a different strain.
Disease severity was also reduced, but the amount of virus remained the same. When S-FLU was administered to ferrets, the viral replication was reduced, as was the amount of virus that was transmitted to other animals. This striking difference in response to the exact same vaccine raises the question whether the ferret, an animal model that is considered gold standard for influenza research, provides results which are transferrable to humans. Pigs provide a model that is more similar in size, naturally infected by influenza viruses and with a very similar respiratory system to humans. The group’s discovery of tissue-resident memory T cell activation in pigs also brings them closer to understanding how influenza is combatted in the lung.
The results also show that targeting the lower respiratory tract with aerosol vaccination in pigs may be more effective than other routes of immunization in preventing severe disease, which provides promising evidence that this method of vaccination could be successful in humans too.
Health, Medicine and Natural Healing 08
Compelling and I haven’t been able to eat pork since. Reading the book because I didn’t want to find myself giving up any. Since many of the glandular-type supplements are derived from pigs, I. haven’t used them. So I’m.
mostly still just using vegetarian products for digestion and adrenal. Not having any remarkable success, especially with the. Then I ran across the argument that pigs are routinely used in testing. As substitutes for people since their make-up is so similar. About that…
we wouldn’t eat humans, but we do use human blood and. Once I’m mentally convinced that a. thing is unhealthy to eat, I become physically ill if I try to eat it,. It gives me just enough improvement to convince me I. need adrenal support, but not enough to actually feel any better.
This is not something I can discuss with my family, since they already. Against, bovine sources, higher quality vegetarian sources…. anything.
pigs – The Farm Barbie – Real Food for Health & Wellness
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The Pirbright Institute
Researchers from The Pirbright Institute collaborated with the University of Oxford and the National Institutes of Health, USA, to show that S-FLU, a universal flu vaccine candidate, induces different immune responses in pigs compared to ferrets, raising the possibility that the ferrets may not give the whole picture and that pigs may more faithfully represent human influenza disease. The team also identified a type of T cell in pigs for the first time, which are able to rapidly help fight respiratory infections.
University of Maryland Extension
4-H members are expected to regularly attend club meetings. BREEDING CAVY. Registration papers must be in the individual 4-Hers name only! Cecil County Fair and Maryland State Fair ownership deadline June 1st of current year. Completed Maryland 4-H Animal Husbandry & Quality Assurance Program by July 1st of current year if 1st year in project or if 4-H age 8, 11 or 14 as of 1/1 of current year.
Intermediates & Seniors-Part 1 and specific project species.
Do pigs eat meat?-About Food & Health
They eat pretty much everything, and anything they can. WHATEVER gets in their way… They will but don’t let a pig get the taste of blood into it’s mouth. It can have damaging affects to the pigs personality as in….once they taste blood they want it again and can actually become very aggressive.
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