Short Term Health Plans Republicans were able to fight off Democratic efforts to roll back a Trump regulation that would expand the number of health insurance plans that don’t have to meet Obamacare’s benefit rules, Alex Ruoff reports. Trump’s Health Team President Trump took a lap in the winner’s circle this week when he signed two bills into law that end pharmacy gag clauses. Pharmacists couldn’t tell a customer if their drugs would be cheaper if they paid without insurance unless the customer explicitly asked. Trump said he expects an immediate impact and that drug costs at the pharmacy counter will go down. Experimental Bundles Over 1,500 hospitals and physician practices are going to be guinea pigs for a new Medicare payment model, James Swann writes.
The Little Guy CVS Health Corp.’s $68 billion merger with Aetna Inc. spells trouble for any other pharmacy benefit service looking to set up shop, Eleanor Tyler reports. Small insurers will also be strained because of the deal because CVS will likely pass on its savings to the insurer and charge full freight for its pharmacy benefit manager work to other carriers. Six Former Pharmacy Employees You might remember when 753 people got sick and 64 died from a contaminated drug that was created in a Massachusetts compounding pharmacy in 2012. Six people involved in that bad batch of medicine will head to court soon, and prosecutors are trying to prove they knowingly marketed non-sterile drugs, Adrianne Appel reports.
Compounded drugs are personalized formulas mixed in-house and sold in very small batches. They’re in a regulatory gray area, which creates concern among some FDA officials that they’re more likely to be tainted than other drugs. The pharmacy, New England Compounding Center, folded long ago, and some people involved in the outbreak have already gone to jail.
Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic.
Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic. Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. Over 30 years ago Professor David Barker first proposed the theory that events in early life could explain an individual’s risk of non-communicable disease in later life: the developmental origins of health and disease hypothesis. During the 1990s the validity of the DOHaD hypothesis was extensively tested in a number of human populations and the mechanisms underpinning it characterised in a range of experimental animal models. Over the past decade, researchers have sought to use this mechanistic understanding of DOHaD to develop therapeutic interventions during pregnancy and early life to improve adult health.
A variety of animal models have been used to develop and evaluate interventions, each with strengths and limitations. It is becoming apparent that effective translational research requires that the animal paradigm selected mirrors the tempo of human fetal growth and development as closely as possible so that the effect of a perinatal insult and/or therapeutic intervention can be fully assessed. The guinea pig is one such animal model that over the past two decades has demonstrated itself to be a very useful platform for these important reproductive studies. This review highlights similarities in the in utero development between humans and guinea pigs, the strengths and limitations of the guinea pig as an experimental model of DOHaD and the guinea pig’s potential to enhance clinical therapeutic innovation to improve human health.
Guinea Pigs Love a Routine
Guinea pigs soon get used to a routine, and will reward you with welcoming squeaks as soon as they hear you open your back door. It is important to check on your guinea pigs at least twice a day, in the morning and evening. Guinea pigs love human company and the more time you can spend with them the happier they are. FeedingGuinea pigs are never happier then when they are eating, and feed time will be rewarded with the loudest squeaks of all. In the morning they should be given a bowl of dry mix, and a variety of fresh food.
During the day if they are in their Eglu they will graze grass, and then in the evening they can be given some fresh hay for overnight. Fresh waterWater is extremely important, and the bottle should be refilled daily. If the weather is cold, be aware that their water could freeze, and may need to be thawed and refilled more frequently. Keep their home clean and tidyHousekeeping is very important, and their bedding should be changed regularly. Unlike rabbits, guinea pigs cannot be trained to use a litter tray, they will toilet anywhere, but the eglu is quick and easy to clean.
The ideal home for your guinea pig
Guinea pigs are very active animals and you’ll need to provide them with lots of toys and objects to keep them active. They’ll need a lot of space to be happy and healthy. A large hutch and a big, grassy exercise area provide them with the ideal living area. They can live indoors or outdoors, so long as they have enough space and are kept comfortable in summer heat or bad winter weather. You can even keep your guinea pigs in a heated outhouse in a cavvycage.
If your guinea pigs live outdoors, don’t let them exercise in bad weather. Consider keeping them in a warm shed or outbuilding where they can exercise indoors during winter. The RSPCA recommends an absolute minimum size of 4ft by 2ft but the bigger the better. Make sure it’s weatherproof and raised off the ground. Guinea pigs don’t sleep much but take naps throughout the day and night.
They’ll need to be able to choose when to go to bed and when to be active. Plenty of toys and activities to keep them entertained.